The present study is aimed at examining the unsteady MHD heat and mass flow of a nanofluid passing a stretching sheet with thermal radiation in a rotating system. The governing boundary layer equations as continuity, momentum, energy, concentration equation were solved by introducing a time dependent length scale in a similarity approach. Obtained nonlinear coupled equations along with the appropriate boundary conditions are then solved by Nactsheim-Swigert shooting iteration technique together with Runge-Kutta six order scheme. The effect of different dimensionless parameters on the flow field as magnetic parameter, rotational parameter, radiation parameter, Prandtl number, Eckert number, Lewis number, Brownian motion parameter, thermophoresis parameter was investigated. The distribution of the primary velocity, secondary velocity, temperature, concentration, local skin-friction coefficients, Nusselt number and the Sherwood number with the effect of the important parameters entering into the problem separately and reported graphically.